How PicoSure Removes Semi Permanent Tattoo Pigment

First published: 2020-08-12 / Last reviewed: 2026-05-28

This is a guide to PicoSure semi-permanent tattoo removal compiled by Dr. Choi Byeong-geun of SHINE U Clinic Konkuk (3 minutes walk from Konkuk Univ. Station Exit 1).

There are more things to consider when removing semi-permanent tattoos or tattoos on eyebrows, eyelines, and underlines than when getting them. This is because the treatment direction varies depending on the type and depth of the pigment and skin type. In this article, we calmly explain how the PicoSure laser breaks down pigments, the treatment process, and management points.

Tattoos and semi-permanent makeup are procedures that embed insoluble pigments deep into the dermis. When pigments such as carmine, indigo, vermilion, and cadmium, or ink, settle in the dermis, natural excretion is difficult.

• Pigments are fixed in the dermis as if stamped, remaining over time.
• Pigments can change and appear as a different color than the original.
• This is why removal is more difficult than application.

PicoSure is an Alexandrite laser that achieves picosecond-level pulses, which are shorter than existing nanosecond lasers.

By targeting the pigmented area with fast and strong energy, the pigment is broken down into smaller particles, making it easier for the broken-down particles to be excreted through the lymphatic vessels.

PicoSure is reported to selectively target pigments injected into the dermis, thereby minimizing damage to surrounding normal skin. Thanks to this, pain is also relatively low, and cases of feeling changes with fewer sessions than before are reported. However, results may vary depending on the individual.

The process proceeds in the following stages:

1. Pigment particles in the epidermis are irradiated with a laser and finely broken down.
2. The finely fragmented pigments are irradiated again to break them down further, and some are excreted through the lymphatic vessels.
3. The smallest fragmented pigments are excreted through the lymphatic vessels and then through urine.

By repeating this process, the pigment gradually fades.

Eyebrows, eyelines, and underlines are sensitive areas.

• It is recommended to undergo treatment at a facility equipped with verified laser devices.
• The procedure must be carried out meticulously, considering the type and depth of the pigment along with the skin type.
• If the semi-permanent makeup shape does not suit your face shape or creates a strong impression, you may consider removal.

If you are curious whether your pigment condition is suitable for removal, check by consulting for semi-permanent makeup removal.

After the procedure, pinpoint bleeding or blisters may appear as pigment particles are destroyed.

• Manage with ointment application or regenerative tape.
• If symptoms are severe, it is advisable to visit the clinic for consultation.
• PicoSure is classified as an FDA-approved device in the United States.

The options vary depending on the type of pigmentation concern.

• For general tattoo removal, please refer to PicoSure Tattoo Removal.
• For improving pigmentation such as melasma and blemishes, PicoSure toning may be helpful.

Rather than neglecting unwanted semi-permanent makeup or tattoos, it is advisable to calmly explore methods suitable for your pigment condition. Since the appropriate approach differs depending on the area and pigment, please feel free to inquire by asking about my semi-permanent makeup removal method.

Authored by: Dr. Choi Byeong-geun (Chief Director of SHINE U Clinic Konkuk / Member of the Korean Laser Dermatology and Hair Society, Korean Society for Aesthetic Plastic Surgery and Laser Medicine, Korean Filler Society, etc.) Last Reviewed: 2026-05-28

This article provides general procedure information and does not replace diagnosis or treatment. The suitability and results of the procedure may vary depending on the individual.