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Spot Fat and Lipolysis Shots GPL and HPL

We have summarized how fat-dissolving injections GPL and HPL each work when only one area does not lose weight even with exercise and diet.

Spot Fat and Lipolysis Shots GPL and HPL
Table of Contents

First published 2024-10-09 / Last reviewed 2026-05-28

This is a guide to Bodyline Cut Injections compiled by Dr. Choi Byeong-geun of SHINE U Clinic Konkuk (3 minutes walk from Konkuk Univ. Station Exit 1).

Many people worry that certain areas of their body just won't slim down, even with exercise and diet control. I was one of them. While looking for methods to approach different body areas, I learned about fat-dissolving injections. I then researched the ingredients and principles and received a consultation.

Reasons for localized fat accumulation

Areas where fat accumulates intensively were difficult to manage with just exercise or diet. There were individual differences, such as:

  • Different upper/lower body fat distribution depending on congenital constitution
  • Influence of prolonged sitting or poor posture
  • A tendency for one specific area to be particularly stubborn

If specific areas like the arms or thighs don't slim down, a targeted approach for that area was necessary.

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Comparing the roles of two ingredients

The differences between the two ingredients, as I learned during my consultation, were as follows:

CategoryGPLHPL
Key IngredientAminophyllineHarmless drugs for the human body
ActionDestroys fat cells and celluliteBreaks down cells through osmosis
Related factorsImproves lymphatic circulationExcreted through urine and sweat

Even though they are both fat-dissolving injections, their mechanisms of action differ, and the key was that the composition varied depending on the individual's condition.

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Cellulite addressed by GPL

GPL contains aminophylline, which targets fat cells and surrounding cellulite that you wish to treat. It works by loosening and gradually breaking down hardened fat and cellulite tissue, while also improving lymphatic circulation, which affects swelling. Since it doesn't require anesthesia, it was easy to receive, and returning to daily life was quick.

If you have concerns about localized fat, please inquire first via consultation chat.

HPL's osmotic principle

HPL uses the principle of osmosis to inject medication into hardened fat layers and break down cells. The broken-down fat cells are then naturally expelled through urine or sweat. This helped reduce body size and refine the overall body line. However, the degree of results may vary among individuals.

Number of shots and cycle depend on your condition

The number of shots may vary depending on skin condition and the area, so it was important to receive guidance on the care cycle and number of shots after assessing individual conditions, rather than a uniform prescription. The key was to plan the treatment according to the area and body type, even for the same injection. You can receive information on costs after a consultation.

If you are concerned about stubborn localized fat, check the customized composition for you through a consultation. You can also explore Body Power Perfect Injections or Body Onda, which may be helpful to consider together.


Authored by: Dr. Choi Byeong-geun (Chief Director of SHINE U Clinic Konkuk / Member of Korean Society for Laser Dermatology and Hair, Korean Academy of Aesthetic Plastic Surgery and Laser Medicine, Korean Academy of Fillers, etc.) Last reviewed: 2026-05-28

This article provides general information about procedures and does not replace diagnosis or treatment. Suitability and results of procedures may vary by individual.

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